PeptideHub
Home
Peptides
CalculatorProtocolsSchedule
HomePeptidesCalculatorProtocolsSchedule
Back to Encyclopedia
Anti-AgingResearch OnlyIntermediate

Thymalin

Thymalin (Thymic Peptide Complex)

Also known as: Thymalin bioregulator, Thymic extract peptide

Overview

A peptide bioregulator derived from the thymus gland, developed by Russian researchers Khavinson and Morozov. Thymalin restores immune function by supporting T-cell maturation and thymic activity, which naturally decline with age (thymic involution). It has been studied extensively in geriatric populations for its immune-restorative and longevity-promoting effects.

Half-Life
~3-4 hours
Typical Dose
5–10 mg
Frequency
Once daily for 5-10 day cycles
Cycle Length
5-10 days on, 4-6 months off

Administration

IntramuscularSubcutaneous

Benefits

  • Restores age-depleted immune function
  • Supports T-cell maturation and thymic output
  • Reduces incidence of infections in elderly populations
  • Demonstrated mortality reduction in long-term geriatric studies
  • Regulates neuroendocrine and immune system crosstalk

Side Effects

  • Injection site discomfort
  • Rare allergic reactions
  • Mild flu-like symptoms during initial immune activation

Mechanism of Action

  • Promotes differentiation and maturation of T-lymphocytes
  • Restores thymic microenvironment function in aged tissues
  • Modulates cytokine production toward balanced immune responses
  • Supports neuroendocrine-immune axis regulation

Contraindications

  • Organ transplant recipients on immunosuppression
  • Active autoimmune disease flares
  • Pregnancy or breastfeeding

Storage & Reconstitution

Store at 2–8°C (36–46°F) for up to 3 months. Once reconstituted, use within 24 hours.

Common peptide amounts:10 mg

Research Summary

In a landmark 15-year study by Khavinson and colleagues, elderly patients receiving annual courses of thymalin and epithalon showed a 28% reduction in mortality compared to controls, along with significant improvements in immune markers, endocrine function, and cardiovascular health. Thymalin has been used clinically in Russia for over 30 years in immunocompromised and geriatric patients. Western clinical trial data remains limited, but the existing body of research is substantial.

Commonly Stacked With

Anti-AgingEpithalon
Anti-AgingVilon
Anti-AgingPinealon

This information is for educational purposes only. Always consult a qualified healthcare professional before using any peptide.